The current outlook of human papillomavirus and its association with digestive tract cancer

Authors

DOI:

https://doi.org/10.22335/rlct.v13i1.1292

Keywords:

human papillomavirus, gastrointestinal cancers, oncogenesis, viral integration

Abstract

Digestive tract cancers are frequent worldwide, despite efforts to control known predisposing factors, they keep increasing, this fact suggests that human papillomavirus (HPV) may play an important oncogenic role in these pathologies. In order to argue the incidence that HPV has in the genesis of gastrointestinal tract tumors and to determine if it is a possible causal agent, the scientific literature published to date on the subject was reviewed, and was found that 4.5% of all diagnosed cancers correspond to HPV; 12% are extra cervical, 20% esophagus, 31.9% colon adenomas, 43% colorectal adenocarcinoma, and 35% head and neck neoplasms (HNSCC). The types of HPV reported in the digestive tract are 6, 9, 11, 13, 16.18, 20, 24, 25, 30, 33, 51, 54, 57, DL 416, DL 428 and DL 436. Although, the studies show the HPV impact in the oncogenesis and its role as a prognostic marker in some of them, they do not have hard evidence that reveals this relationship, therefore demonstrating its integration would allow clarifying it.

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Author Biographies

  • Isabel Cristina Almonacid Urrego, Policía Nacional de Colombia, Bogotá, Colombia

    Médico Cirujano. Especialista en patología. Magíster Oncología Molecular. Magíster Ginecología Oncológica.

  • Carmen Cecilia Almonacid Urrego, Universidad Colegio Mayor de Cundinamarca, Bogotá, Colombia

    Bacterióloga y Laboratorista Clínico. MSc. Microbiología con énfasis en Bioquímica. PhD Biomedicina.

  • Sonia Marcela Rosas Arango, Universidad Colegio Mayor de Cundinamarca, Bogotá, Colombia

    Bacterióloga y laboratorista clínico. Magíster en Gestión ambiental y auditorias.

  • Edith del Carmen Hernández Rojas, Universidad Colegio Mayor de Cundinamarca, Bogotá, Colombia

    Bacterióloga. Magister en Ciencias- Microbiología- Énfasis biología molecular.

  • Johanna Lizeth González Devia, Universidad Colegio Mayor de Cundinamarca, Bogotá, Colombia

    Bacteriología y laboratorio clínico. Msc Bioquímica.

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Published

2021-01-01

Issue

Section

Review Articles

How to Cite

The current outlook of human papillomavirus and its association with digestive tract cancer. (2021). Revista Logos Ciencia & Tecnología, 13(1), 129-143. https://doi.org/10.22335/rlct.v13i1.1292